Gene Therapy Trial for Usher’s Syndrome To Begin

November 1, 2011

Oxford BioMedica announced that it had gained approval from the FDA to begin a Phase I/IIa Clinical Trial for a form of Usher’s Syndrome, Type 1B, which leads to progressive retinitis pigmentosa combined with a congenital hearing defect.

Usher syndrome is the most common form of deaf-blindness which affects approximately 30,000-50,000 patients in the US and Europe. One of the most common subtypes is Usher syndrome type 1B. The disease is caused by a mutation of the gene encoding myosin VIIA (MY07A).

The open label, dose escalation Phase I/IIa study will enrol up to 18 patients with Usher syndrome type 1B at the Oregon Health and Science University’s Casey Eye Institute, Portland, Oregon. The study, led by Professor Richard Weleber, will evaluate three dose levels for safety, tolerability and aspects of biological activity and is expected to be initiated by the end of 2011.

For more info:

http://irvaronsjournal.blogspot.com/2011/10/gene-therapy-update-1-first-clinical.html

http://eyedocnews.com/006188-gene-therapy-trial-for-retinitis-pigmentosa-based-on-usher%E2%80%99s-syndrome-to-begin/

 


Foundation Fighting Blindness on Facebook

July 4, 2011
Description
The Foundation Fighting Blindness is a publicly-supported charity raising money to fund research for macular degeneration, retinitis pigmentosa (RP), Usher syndrome, Stargardt disease, related diseases, and providing information, resources and referrals.
Address
Phone
800-683-5555
Website
Founded
1971
About
The Foundation Fighting Blindness is dedicated to funding innovative research to find preventions, treatments, and cures for inherited retinal degenerative diseases that lead to blindness and affect more than 10 million people in the United States.
Company Overview
Since its founding in 1971, the Foundation Fighting Blindness has been dedicated to funding innovative research to find preventions, treatments, and cures for inherited retinal degenerative diseases that lead to blindness and affect more than 10 million people in the United States.
Mission
The urgent mission of the Foundation Fighting Blindness, Inc. (FFB) is to drive the research that will provide preventions, treatments and cures for people affected by retinitis pigmentosa (RP), macular degeneration, Usher Syndrome, and the entire spectrum of retinal degenerative diseases.

NoisyVision | Usher Syndrome & more on Facebook

July 4, 2011
Founded
1.1.11
About
or how I learned to stop worrying and love my limits
Company Overview
Noisyvision is a project lead by two Usher Syndrome brothers.
Description
Noisyvision is a project of information and culture.
To say it is a vision sounds ironic, perhaps obvious. But it is a look towards another possibility, a different approach to sensory perception and to overcome difficulties associated with limited eyesight and hearing.

Noisyvision arises from the need to show with IMAGES, WORDS and IDEAS a unique perception of world and life.

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Mission
Noisyvision wants to transform disabilities into something good.
Deafnees and blindness are difficult but still we can learn to hear and see as we can do it with the mind and the hearth
Email
info@noisyvision.com
Website