Nanoparticles Treat Degenerative Eye Disease Without Eye Injections


People with macular degeneration develop a blind or blurry spot at the center of their field of vision, making it difficult for them to read and recognize loved ones’ faces. To slow or reverse this loss of vision, many patients receive monthly injections of an antibody drug directly into their eyes. To find a less invasive treatment, a team of researchers led by Balamurali K. Ambati of the University of Utah has tested biodegradable polymer nanoparticles that deliver a therapeutic gene to eye tissue (ACS Nano, DOI:10.1021/nn305958y). With a single intravenous dose of the particles, the scientists partially restored vision in mice with a model of the disease.

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2 Responses to Nanoparticles Treat Degenerative Eye Disease Without Eye Injections

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