Aspirin and AMD: Confusion, and More Data Needed

Despite its multitude of benefits, aspirin has recently come under fire again because of an association with age-related macular degeneration (AMD). AMD is a leading cause of vision loss in adults in the developed world.[3] Most severe visual loss is associated with the neovascular (wet) form of AMD, and approximately 200,000 new diagnoses are made each year in the United States.[4,5] Wet AMD is characterized by pathologic angiogenesis with abnormal growth of blood vessels under and into the neurosensory retina. These immature blood vessels can rupture and hemorrhage, a potentially devastating event for the retina in terms of visual function.

Because aspirin use and AMD are both common, a potential association between the 2 has been considered in many studies. Two major approaches have been used to study this association: prospective randomized trials and observational trials.

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One Response to Aspirin and AMD: Confusion, and More Data Needed

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