Genes Not Very Helpful in Predicting Age-Related Macular Degeneration

Although there have been studies that take a look at genetic and environmental risk factors for AMD and how they relate, the relationship between these factors had not previously been extensively studied in patients over a long period of time.

The findings of a study by  Dr. Ronald Klein, M.D., M.P.H. of the University of Wisconsin School of Medicine showed that genetic risk factors were not very helpful in terms of predicting the progression and incidence of the disease. Instead, what turned out to be more helpful were actual ophthalmological examinations once early signs of AMD occurred.

“Once the early signs are there, just looking at them ophthalmoscopically will help you estimate development of late AMD much better than the genes themselves. So while the genes are important in terms of understanding causes of the disease, in terms of individual risk assessment, they have less importance at this point in time.”

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