Vascular Treatment to Prevent Progression of Dry AMD

The progressive disease occurs in the dry or early (non-exudative) form and the wet or late (exudative) form. Approximately 30 million people have AMD; 90% of those afflicted have the dry form, for which there is no approved treatment.

Dr. George Chiou determined the way to prevent the progression of dry AMD to wet AMD was to develop formulations that could restore choroidal blood flow, thus returning the natural process of nutrient and waste exchange and stabilization of the Bruch’s Membrane.

MacuCLEAR, Inc. (Plano, Texas) completed a Phase 1b/POC study of a topical agent, MC 1101, that significantly improved choroidal blood flow in eyes affected by AMD.

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