Book Scanning Facility

October 22, 2016

The following is from Lauren Tappan


“Duke University East Campus Library now has the Book Eye 4.
You do not have to be a Duke student to use this
AT equipment.
  You put a book on their scanner and you can scan
this written material to a USB thumb drive or send it
to an e-mail address.
  Quick and easy to use.”

Book > 100 Questions & Answers About Macular Degeneration

October 4, 2016

100 Questions & Answers About Macular Degeneration

Whether you’re a newly diagnosed patient, or a friend or relative of someone suffering with macular degeneration, this book offers guidance and support

This book provides authoritative, practical answers to commonly asked questions about this condition to help you better understand all aspects of dealing with macular degeneration including treatment options, sources of support, and much more. It’s an invaluable resource for anyone coping with the disease’s physical and emotional turmoil.

For more info:

Potential Treatment for RP and AMD

October 4, 2016

New research published in Cell Reports identifies a potential treatment target for blinding diseases such as retinitis pigmentosa and advanced dry age-related macular degeneration. In the study, researchers at Washington University in St. Louis School of Medicine explored how the retina’s photoreceptors — the rods and cones responsible for detecting light, color, contrast, and sharpness — are damaged over the course of these diseases.

Lin, Apte and colleagues at Washington Univ. found that defects in the same NAD pathway appear to be involved in several different diseases of the retina. When they treated damaged photoreceptor cells in mice with a second molecule called NMN — a precursor molecule that boosts levels of NAD — the cells’ degeneration ceased and vision was restored.

“This is exciting because we may have found a reason why these highly metabolically active cells are susceptible to damage and death when the NAD pathway does not function optimally,” said Apte, also a professor of developmental biology and neuroscience and of medicine.

The pathway offers a promising target for therapies for multiple retinal diseases, including retinitis pigmentosa, a cause of blindness that impairs vision over many years and for which there is currently no cure.

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Genetics usually the cause of macular degeneration

October 4, 2016

Genetics play a big role on those who end up with macular degeneration, an eye disease that leads to vision loss.

Vitreoretinal specialist Dr. Mandi D. Conway with Arizona Retinal Specialists in Sun City West said caucasians have a genetic disposition to macular degeneration. In contrast, Hispanics, Native Americans, African Americans or Asians have a lower risk.

However, diet may play an important role in getting macular degeneration Ms. Conway noted. Based on studies, she said some believe that fatty acids on the liver that metabolize have an affect on the retina.

It is also suggested that the blue light emitted from the sun can be a cause of macular degeneration, therefore, Ms. Conway recommends people always wear sunglasses outdoors to help lower the risk.

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AMD Increases Risk of Brain Hemorage

September 24, 2016

Age-related macular degeneration  (AMD) patients are at an increased risk for brain hemorrhage. Study researcher Renske G. Wieberdink, M.D., said, “Other studies have found there are more strokes in older individuals with late AMD, but ours is the first to look at the specific types of strokes. We found the association is with brain hemorrhage, but not brain infarction.”

The study only observed a small amount of brain hemorrhages, so larger studies are needed in order to make any conclusions on the association between the two.

Dr. Wieberdink added, “These findings should be considered preliminary. Patients and physicians must be very careful not to over-interpret them. We don’t know why there are more brain hemorrhages in these patients or what the relationship with AMD might be. This does not mean that all patients with late-stage AMD will develop brain hemorrhage.”

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Copyright Precaution

September 20, 2016

A note from Zoe Chen of Zoomax

Buck Institute finds potential macular degeneration treatment

September 19, 2016

Researchers at the Buck Institute for Research on Aging have found a potential treatment for macular degeneration using a broccoli-related compound.

By injecting it in mice, they found evidence of a possible treatment for the eye disease, which is the leading cause of vision loss affecting more than 10 million Americans.

“We scientists must learn from nature. Nature has come up with these wonderful strategies to detoxify our bodies,” said Arvind Ramanathan, an assistant professor at the Novato-based Buck Institute and lead author of the study, which was published in the journal Scientific Reports in July.

The road to creating an FDA-approved drug is long. Ramanathan estimated that if the Buck Institute can get a grant from the National Institutes of Health to work on more aspects of the compound, “I would hope in the next five years we would move into a clinical phase,” meaning testing of the potential drug.

It would still be years after that before the drug could come to market, but the work of Ramanathan and his colleagues gives hope to the millions of Americans who are affected by macular degeneration or at risk for the disease.

With this in mind, Ramanathan and his team set out to find a compound “that acts like indole, but only better.” After running a computer search of millions of compounds, “we found a compound like this, but it was 10 times more potent in detoxification.”

The compound is known in short form as 2AI.

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